Octopus UK “megatrial” will test existing drugs as new treatments for MS


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A broad-reaching trial of already-approved drugs is hoped to turn up new treatment options for people with progressive forms of MS. Octopus Study to Test Drug Effects on Progressive MS


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Inside the MS Octopus mega-trial: inspired by cancer, supported by patients Features Inside the MS mega-trial: inspired by cancer, supported by patients The UK MS Society discusses how it plans to research treatments for progressive MS. Kezia Parkins June 23, 2021


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Octopus is a revolutionary trial that will transform the way we test treatments for progressive MS. A smarter way of testing potential treatments, it could deliver life-changing new treatments up to three times faster. The trial team have now confirmed the first treatments they'll be testing .


Octopus UK “megatrial” will test existing drugs as new treatments for MS

This is a real unmet need for people living with MS, many of whom have no treatments to slow disability progression at the moment. The Octopus trial is designed to slot in new drugs asthey're discovered. We hope that Octopus will test more drugs - or combinations of drugs - that can stop progression of the disease altogether, and even one.


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Octopus is a revolutionary trial that will transform the way we test treatments for progressive MS. A smarter way of testing potential treatments, it could deliver life-changing new treatments up to three times faster.


Octopus Free Stock Photo Public Domain Pictures

Octopus is a clinical trial evaluating several potential treatments for primary and secondary progressive multiple sclerosis (MS).


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Octopus is a trial which will test multiple treatments with the aim to find one that can slow down, and ultimately stop, the progression of disability in people with primary or secondary progressive MS. Octopus aims to be a more efficient kind of clinical trial by using the multi-arm, multi-stage (MAMS) approach, visit this page about MAMS for.


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OCTOPUS is the first MS trial to use a type of trial design known as multi-arm multi-stage (MAMS). This method can have many advantages over traditional trials: It allows several treatments to be tested at the same time against a common control (i.e. "multi-arm"). Treatments which appear to be effective from the early data can continue onto.


Octopus trial one step closer to launch MS Society

Octopus is a revolutionary trial that will transform the way we test treatments for Progressive Multiple Sclerosis (MS). A smarter way of testing potential treatments, it could deliver life-changing new treatments up to three times faster. Octopus is now open to recruitment!


Why we need to find treatments for progressive MS MS Society's Octopus trial YouTube

Launched in April 2023, Octopus is a revolutionary MS clinical trial that will transform the way we test treatments for progressive MS. The trial is devised to be smarter than the current standard style of clinical trial.


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The Octopus trial - so-called because it is a multi-arm, multi-stage trial - is being run by Prof Jeremy Chataway, from the National Hospital for Neurology and Neurosurgery UCLH in London,.


'Major moment in MS research' as new Octopus trial starts Lounge

Introducing Octopus - the world's first multi-arm, multi-stage trial for MS Tuesday 4 May 2021 We're pleased to introduce Octopus - our revolutionary, multi-arm, multi-stage trial that will transform the way we test treatments for progressive MS.


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The Octopus MS clinical trial is the first multi-arm, multi-stage trial for MS. The trial is led by researchers at University College London and is currently testing two drugs already used in other conditions against a placebo (dummy drug). These are metformin and alpha lipoic acid.


Octopus inside the progressive MS megatrial VJNeurology

4 April 2023 The first patients have been recruited for a revolutionary trial, led by UCL researchers, that will transform the way that treatments are tested for progressive multiple sclerosis (MS). Octopus is a world-first clinical trial, funded by the MS Society and led by researchers at the MRC Clinical Trials Unit at UCL.


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Jeremy Chataway, MA, PhD, FRCP, UCL Institute of Neurology, London, UK, gives an insight into the Octopus trial, the first-ever multi-arm, multi-stage (MAMS).


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The Octopus trial is led by Prof Jeremy Chataway at University College London (UCL). Along with the trial site at UCL Queen Square Institute of Neurology, the Anne Rowling Clinic is now open for recruitment. The Octopus trial management team have plans to open 30 Octopus trial sites across the UK. The Anne Rowling Regenerative Neurology Clinic.